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hSMART
human Sensor for MLKL Activation by RIPK3 based on FRET
MLKL
binding
Unimolecular
FRET
N/A
YPet | hMLKL alpha helix 1 | SAGG linker | hMLKL alpha helix 2 | SAGG linker | hMLKL alpha helix 3-5 | ECFP
hMLKL alpha helicies
YPet | ECFP
Senses MLKL oligomerization. Works in human cells. For mouse cells see mSMART