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Biosensor Name (short):
FLLIP
Long name :
fluorescent indicator for a lipid second messenger that can be tailor-made
Biosensor Target:
PIP3
Sensing Type:
binding
Number of Molecules:
Unimolecular
Physics Type:
FRET
Biosensor Group:
FLLIP
Biosensor Sub-group:
N/A
Sensor Components:
CFP | PH domain from GRP1 which selectively binds PtdInsP3 | YFP | alpha-helical linkers consisting of repeated EAAAR sequences | Membrane localization sequence
Sensing Element:
PH domain from GRP1 which selectively binds PtdInsP3
Source Pubmed ID:
14528311 [Pubmed]
Fluorescent Proteins:
CFP | YFP
Addgene Plasmid #:
Subcellular Targeting :
Other Source Pubmed IDs:
Notes: