FLLIP - PIP3 Fluorescent Biosensor Details

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Biosensor Name (short):

FLLIP

Long name :

fluorescent indicator for a lipid second messenger that can be tailor-made

Biosensor Target:

PIP3

Sensing Type:

binding

Number of Molecules:

Unimolecular

Physics Type:

FRET

Biosensor Group:

FLLIP

Biosensor Sub-group:

N/A

Sensor Components:

CFP | PH domain from GRP1 which selectively binds PtdInsP3 | YFP | alpha-helical linkers consisting of repeated EAAAR sequences | Membrane localization sequence

Sensing Element:

PH domain from GRP1 which selectively binds PtdInsP3

Source Pubmed ID:

14528311 [Pubmed]

Fluorescent Proteins:

CFP | YFP

Addgene Plasmid #:

Subcellular Targeting :

Other Source Pubmed IDs:

Notes: