Nano-lantern cAMP1.6 - cAMP Fluorescent Biosensor Details

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Biosensor Name (short):

Nano-lantern cAMP1.6

Long name :

Biosensor Target:

cAMP

Sensing Type:

binding

Number of Molecules:

Unimolecular

Physics Type:

Bioluminescence

Biosensor Group:

Nano-lantern cAMP

Biosensor Sub-group:

N/A

Sensor Components:

Venus delta C10 | N-RLuc8 delta N3 (4-228) | EPAC1 (G170-A327) Q270E| C-RLuc8 (229-311) S257G

Sensing Element:

EPAC1 (G170-A327) Q270E

Source Pubmed ID:

23232392 [Pubmed]

Fluorescent Proteins:

Venus delta C10 | N-RLuc8 delta N3 (4-228) | C-RLuc8 (229-311) S257G

Addgene Plasmid #:

Addgene #53591

Subcellular Targeting :

Other Source Pubmed IDs:

Notes:

Split Luciferase complimentation also can do BRET. Also has variants of cAMP0.4 and cAMP3.3 that are associated with domains with 0.4 and 3.3 uM affinity